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KMID : 0616120110420010054
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Korean Journal of Pharmacognosy
2011 Volume.42 No. 1 p.54 ~ p.60
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The Extract of Aster glehni Leaves Rich in Caffeoylquinic Acids Prevents Atherogenic Index, Oxidative Stress, and Body Weight Increase in High-Fat Diet-induced Rats
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Kim Myung-Hoe
Nugroho Agung
Choi Jong-Won
Park Hee-Juhn
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Abstract
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In an attempt to find the activity of Aster glehni (Compositae) leaves on the obesity in vivo, 30% ethanolic extract rich in caffeoylquinic acids was orally treated with 100 and 200 mg/kg for consecutive four weeks during feeding high-fat diet in rats for 6 weeks. This extract prevented the increase of atherogenic index and body weight and oxidative stress from dietinduced obese rats probably due to the pharmacological mechanism of the CQ complex.
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KEYWORD
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Aster glehni, Compositae, Caffeoylquinic acid, High-fat diet, Atherogenic index, Oxidative stress
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